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Valerian E Kagan Selected Research

Proteins (Proteins, Gene)

1/2021A new thiol-independent mechanism of epithelial host defense against Pseudomonas aeruginosa: iNOS/NO• sabotage of theft-ferroptosis.
1/2019Mitochondria modulate programmed neuritic retraction.
11/2016Isolation of human trophoblastic extracellular vesicles and characterization of their cargo and antiviral activity.
3/2014Oxidized lipids block antigen cross-presentation by dendritic cells in cancer.
2/2011Normoxic versus hyperoxic resuscitation in pediatric asphyxial cardiac arrest: effects on oxidative stress.
1/2009Starving neurons show sex difference in autophagy.
9/2007Hemigramicidin-TEMPO conjugates: novel mitochondria-targeted anti-oxidants.
6/2007Vitamin E deficiency enhances pulmonary inflammatory response and oxidative stress induced by single-walled carbon nanotubes in C57BL/6 mice.
4/2007Neuronal NOS-mediated nitration and inactivation of manganese superoxide dismutase in brain after experimental and human brain injury.
9/2005Cytochrome c acts as a cardiolipin oxygenase required for release of proapoptotic factors.
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Valerian E Kagan Research Topics

Disease

27Neoplasms (Cancer)
01/2022 - 01/2008
22Traumatic Brain Injuries (Traumatic Brain Injury)
01/2022 - 05/2002
19Inflammation (Inflammations)
01/2022 - 03/2007
10Pneumonia (Pneumonitis)
11/2017 - 11/2005
7Infections
01/2022 - 12/2005
6Alzheimer Disease (Alzheimer's Disease)
01/2021 - 01/2008
6Lung Injury
11/2017 - 01/2005
6Parkinson Disease (Parkinson's Disease)
02/2014 - 06/2004
5Reperfusion Injury
01/2022 - 11/2005
5Brain Injuries (Brain Injury)
01/2019 - 04/2007
5Heart Arrest (Cardiac Arrest)
01/2019 - 01/2002
5Acute Lung Injury
04/2014 - 01/2005
4Asthma (Bronchial Asthma)
01/2022 - 06/2014
4Ischemia
01/2021 - 02/2007
4Mitochondrial Diseases (Mitochondrial Disease)
01/2019 - 03/2005
4Fibrosis (Cirrhosis)
01/2017 - 06/2007
4Hemorrhagic Shock
01/2008 - 11/2002
3Granuloma
10/2017 - 11/2005
3Carcinoma (Carcinomatosis)
05/2015 - 05/2002
3Cadaver (Cadavers)
01/2014 - 01/2005
3Hypothermia
01/2010 - 01/2002
3Pre-Eclampsia (Preeclampsia)
08/2008 - 01/2005
2Blister (Bulla)
01/2022 - 11/2016
2Sepsis (Septicemia)
01/2021 - 10/2009
2Hypoxia (Hypoxemia)
11/2020 - 05/2010
2Rupture
10/2020 - 03/2012
2Infarction (Infarctions)
01/2019 - 05/2010
2Neuroblastoma
01/2018 - 01/2016
2Bacterial Pneumonia
11/2017 - 10/2010
2Chronic Disease (Chronic Diseases)
10/2017 - 09/2007
2Pulmonary Fibrosis (Fibrosing Alveolitis)
10/2017 - 04/2014
2Wounds and Injuries (Trauma)
10/2017 - 09/2015
2Necrosis
01/2016 - 04/2011
2Melanoma (Melanoma, Malignant)
05/2015 - 03/2009
2Hyperplasia
06/2014 - 03/2012
2Lung Diseases (Lung Disease)
04/2014 - 04/2014
2Memory Disorders (Memory Loss)
06/2013 - 01/2009
2Lewis Lung Carcinoma
05/2013 - 11/2011
2Lung Neoplasms (Lung Cancer)
11/2011 - 05/2002
2Glioblastoma (Glioblastoma Multiforme)
10/2010 - 10/2009
2Hyperoxia
07/2010 - 09/2009

Drug/Important Bio-Agent (IBA)

22LipidsIBA
01/2022 - 09/2007
16Cardiolipins (Cardiolipin)IBA
01/2019 - 09/2005
13Phospholipids (Phosphatides)FDA LinkGeneric
01/2022 - 09/2005
12Proteins (Proteins, Gene)FDA Link
01/2021 - 05/2002
12AntioxidantsIBA
01/2021 - 01/2002
11Peroxidase (Myeloperoxidase)IBA
10/2020 - 08/2008
11Reactive Oxygen Species (Oxygen Radicals)IBA
01/2019 - 04/2002
11Carbon Nanotubes (Carbon Nanotube)IBA
10/2017 - 06/2007
7Pharmaceutical PreparationsIBA
11/2020 - 01/2002
7CytokinesIBA
04/2014 - 12/2005
7PhosphatidylserinesIBA
01/2014 - 05/2002
6EnzymesIBA
10/2020 - 08/2008
6AntigensIBA
01/2020 - 03/2009
6Cytochromes c (Cytochrome c)IBA
11/2014 - 01/2008
5Biomarkers (Surrogate Marker)IBA
11/2020 - 07/2012
5Fatty Acids (Saturated Fatty Acids)IBA
11/2020 - 01/2009
5CollagenIBA
10/2017 - 06/2007
5nitroxylIBA
02/2015 - 01/2008
4Glutathione (Reduced Glutathione)IBA
01/2022 - 07/2010
4Oxygen (Dioxygen)IBA
09/2018 - 07/2010
3phosphatidylethanolamineIBA
01/2022 - 01/2019
3Phospholipases (Phospholipase)IBA
11/2020 - 02/2015
3Adenosine Triphosphate (ATP)IBA
01/2016 - 03/2005
3Peptides (Polypeptides)IBA
03/2014 - 09/2007
3Oxidopamine (6 Hydroxydopamine)IBA
02/2014 - 11/2005
3Triglycerides (Triacylglycerol)IBA
09/2011 - 01/2009
3S-nitrosoalbuminIBA
04/2011 - 01/2003
3TEMPOIBA
10/2010 - 02/2007
3XJB-5-131IBA
07/2010 - 09/2007
3Gramicidin (Gramicidin A)FDA LinkGeneric
07/2010 - 09/2007
3Dopamine (Intropin)FDA LinkGeneric
06/2006 - 06/2004
3tempolIBA
11/2005 - 01/2002
2Phosphotransferases (Kinase)IBA
01/2022 - 04/2014
2Lipoproteins (Lipoprotein)IBA
01/2021 - 01/2006
2Vitamin EFDA LinkGeneric
01/2021 - 06/2007
2Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA
01/2021 - 10/2017
2Heme Oxygenase-1IBA
01/2021 - 03/2012
2CalciumIBA
11/2018 - 02/2015
2Paclitaxel (Taxol)FDA LinkGeneric
09/2018 - 01/2015
2Etoposide (VP 16)FDA LinkGeneric
01/2018 - 03/2011
2Nonesterified Fatty Acids (NEFA)IBA
10/2017 - 12/2012
21-Alkyl-2-acetylglycerophosphocholine Esterase (PAF Acetylhydrolase)IBA
01/2016 - 12/2012
2Peroxynitrous Acid (Peroxynitrite)IBA
05/2015 - 03/2005
2Caspase 3 (Caspase-3)IBA
02/2015 - 07/2010
2CopperIBA
07/2014 - 01/2005
2Silicon Dioxide (Silica)FDA LinkGeneric
04/2014 - 11/2005
2AsbestosIBA
01/2014 - 04/2012
2ChemokinesIBA
06/2013 - 05/2008
2Oxidants (Oxidizing Agents)IBA
04/2011 - 03/2005
23-nitrotyrosineIBA
02/2011 - 04/2007
2Superoxide DismutaseIBA
02/2011 - 04/2007
2SynucleinsIBA
01/2010 - 06/2009

Therapy/Procedure

17Therapeutics
01/2022 - 11/2002
5Immunotherapy
01/2022 - 03/2009
5Resuscitation
01/2019 - 11/2002
2Cardiopulmonary Bypass (Heart-Lung Bypass)
01/2020 - 01/2002
2Radiotherapy
01/2017 - 11/2011
2Cardiopulmonary Resuscitation (CPR)
02/2015 - 02/2011
2Induced Hypothermia
01/2010 - 02/2009